The International Committee for the History of Technology’s 49th Symposium is hosted by the University of Ostrava, Czech Republic. Since it will take place online it is scheduled in two slots: 24th–25th September and 15th–16th October 2022. The general theme is “Technology-based and Technology-generated decisions”. Whereas technology-based decisions have a long history, technology-generated decisions of so-called artificial intelligence, AI, are on the horizon since the turn of the 21st century and might gain decisive influence within the next years. Which decisions we are willing to hand over to technology? How to define ethical guidelines for this development? The symposium aims to contribute to this discussion, based on a transnational perspective of the history of technology. * * * Caption: Marie Ebner-Eschenbach (formerly owned by), Andreas Hohenadel (watchmaker), pocketwatch „Nr. 996“ by Andreas Hohenadel, Wien, 1780–1793, Wien Museum Inv.-Nr. U 1486, CC BY 4.0, photography: Birgit and Peter Kainz, Wien Museum (https://sammlung.wienmuseum.at/objekt/389659/).